Organization profile

Organisation profile

The Institute of Medical Sciences is home to Principal Investigators leading cutting edge molecular and cell biology research in a variety of fields.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Candida albicans Medicine & Life Sciences
Genes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Schizophrenia Medicine & Life Sciences
Cell Wall Medicine & Life Sciences
Virulence Medicine & Life Sciences
Infection Medicine & Life Sciences
Genome Medicine & Life Sciences

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Research Output 1979 2019

Alternative (backdoor) androgen production and masculinization in the human fetus

O'Shaughnessy, P. J., Antignac, J-P., Le Bizec, B., Morvan, M-L., Svechnikov, K., Söder, O., Savchuk, I., Monteiro, A., Soffientini, U., Johnston, Z. C., Bellingham, M., Hough, D., Walker, N., Filis, P. & Fowler , P. 14 Feb 2019 In : PLoS Biology. 17, 2, e3000002

Research output: Contribution to journalArticle

Open Access
File
androsterone
Androsterone
masculinization
androgens
Androgens

A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Hwang, D-J., He, Y., Ponnusamy, S., Mohler, M. L., Thiyagarajan, T., McEwan, I. J., Narayanan, R. & Miller, D. D. 2019 In : Journal of Medicinal Chemistry. 62, 2, p. 491-511 20 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Castration
Cyclization

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Warren, A. Y. , Massie, C. E. , Watt, K. , Luko, K. , Orafidiya, F. , Selth, L. A. , Mohammed, H. , Chohan, B. S. , Menon, S. , Baridi, A. , Zhao, W. , Escriu, C. , D'Santos, C. , Taylor, C. , Qureshi, A. , Zecchini, V. R. , Shaw, G. L. , Dehm, S. M. , Mills, I. G. , Carroll, J. S. & 5 others Tilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M. 2019 In : Oncogene. 38, p. 1136-1150 15 p.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Prostatic Neoplasms
PDZ-binding kinase
Systems Biology
Proteome

Equipment

Electron Microscopy

Debbie Isabelle Wilkinson (Manager)

Institute of Medical Sciences

Facility/equipment: Facility

Electron Microscopy
Freeze Substitution
Equipment and Supplies
Scanning Transmission Electron Microscopy
Vacuum
Single-Cell Analysis
Financial Management
Cell Tracking
Eye Diseases
Genomics
peptides
antibodies
screening
industries
proteins

Prizes

Academic Gold Medal of the Institute of Physics and Engineering in Medicine

David John Lurie (Recipient), 13 Sep 2017

Prize: Prize (including medals and awards)

gold
physics
biology
medicine
engineering

Berkeley Award

Pieter Van West (Recipient), 6 Dec 2002

Prize: Prize (including medals and awards)

mycology

"Best Poster" on new insights into cardiovascular-brain interactions

Vesna Vuksanovic (Recipient), 2016

Prize: Prize (including medals and awards)

Activities 2003 2018

3R&3C Symposium 2018

Hiraga, S. (Speaker)
12 Nov 201816 Nov 2018

Activity: Conference

Antimicrobial resistance conference

Palliyil, S. S. (Speaker)
26 Apr 2018

Activity: Conference

Press / Media

Boost to battle blindness

Heather M Wilson

12/07/18

1 media contribution

Press/Media: Research

New funding awarded to battle blindness

Heather M Wilson

5/07/18

1 item of media coverage

Press/Media: Research