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Thomas Baddeley

Dr

    • 162 Citations
    20012020

    Research output per year

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    Research Output

    • 162 Citations
    • 25 Article
    • 3 Patent
    2020

    Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

    Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 19 May 2020, In : Journal of Alzheimer's Disease. 75, 2, p. 501-519 19 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    1 Citation (Scopus)
    1 Downloads (Pure)
    2019

    Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease

    Schelter, B. O., Shiells, H. C., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Riedel, G., Gauthier, S., Jia, J., Bentham, P., Kook, K., Storey, J. M. D., Harrington, C. R. & Wischik, C. M., 26 Nov 2019, In : Journal of Alzheimer's Disease. 72, 3, p. 931-946 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    6 Citations (Scopus)
    6 Downloads (Pure)
    Open Access
    File
    3 Downloads (Pure)

    Synthesis, potent anti-TB activity against M. tuberculosis ATTC 27294, crystal structures and complex formation of selected 2-arylidenehydrazinylbenzothiazole derivatives

    Pinheiro, A. C., de Souza, M. V. N., Lourenco, M. C. S., da Costa, C. F., Baddeley, T. C., Low, J. N., Wardell, S. M. S. V. & Wardell, J. L., 15 Feb 2019, In : Journal of Molecular Structure. 1178, p. 655-668 14 p.

    Research output: Contribution to journalArticle

    2 Citations (Scopus)
    2018
    Open Access
    File
    9 Citations (Scopus)
    13 Downloads (Pure)
    2 Citations (Scopus)

    Cysteine-independent inhibition of Alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT)

    Al-Hilaly, Y. K., Pollack, S. J., Rickard, J. E., Simpson, M., Raulin, A-C., Baddeley, T., Schellenberger, P., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 19 Oct 2018, In : Journal of Molecular Biology. 430, 21, p. 4119-4131 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    7 Citations (Scopus)
    10 Downloads (Pure)
    2017

    Crystal structures of four 1-(aryl)-[1,2,4]triazolo[4,3-a]quinoxaline derivatives

    Nogueira, T. C. M., Pinheiro, A. C., de Souza, M. V. N., Baddeley, T. C., Wardell, J. L. & Wardell, S. M. S. V., 15 Jan 2017, In : Journal of Molecular Structure. 1128, p. 579-589 11 p.

    Research output: Contribution to journalArticle

    In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

    Steven, J., Müller, M. R., Carvalho, M. F., Ubah, O. C., Kovaleva, M., Donohoe, G., Baddeley, T., Cornock, D., Saunders, K., Porter, A. J. & Barelle, C. J., 23 Oct 2017, In : Frontiers in Immunology. 8, 1361.

    Research output: Contribution to journalArticle

    Open Access
    File
    10 Citations (Scopus)
    6 Downloads (Pure)
    2015
    64 Citations (Scopus)
    2012

    1,3-Diphenyl-4,5-dihydro-1H-pyrazol-5-one

    Baddeley, T., Wardell, S. M. S., Tiekink, E. & Wardell, J., Apr 2012, In : Acta Crystallographica Section E: Structure Reports Online. E68, p. o1016-o1017 2 p.

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Variation in supramolecular arrangements of hydrazones, o-H2NC6H4CMe=NNHC6H4X (X = H, o-, m- and p-NO2), derived from o-aminoacetophenone and phenylhydrazines

    Howie, R. A., Baddeley, T. C., Wardell, J. L. & Wardell, S. M. S. V., 8 Aug 2012, In : Journal of Molecular Structure. 1020, p. 16-22 7 p.

    Research output: Contribution to journalArticle

    5 Citations (Scopus)
    2011
    File
    10 Downloads (Pure)
    2009

    2-Hydroxyacetophenone arylhydrazones. Supramolecular arrangements based on C–H · · · O(H), CH · · · O(NO), N–H · · · O(H), N–H · · · O(NO), C–H · · · π or π · · · π interactions

    Baddeley, T. C., Franca, L. D. S., Howie, R. A., de Lima, G. M., Skakle, J., de Souza, J. D., Wardell, J. L. & Wardell, S. M. S. V., Sep 2009, In : Zeitschrift für Kristallographie. 224, 4, p. 213-224 12 p.

    Research output: Contribution to journalArticle

    13 Citations (Scopus)
    8 Citations (Scopus)
    2006

    A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

    Kyeremeh, K., Baddeley, T., Stein, B. K. & Jaspars, M., 2006, In : Tetrahedron. 62, p. 8770-8778 9 p.

    Research output: Contribution to journalArticle

    18 Citations (Scopus)
    2005
    4 Citations (Scopus)
    2004

    Supramolecular structures of substituted a,a'-trehalose derivatives

    Baddeley, T., Wardell, J. L., Skakle, J., Low, J., Glidewell, C. & Davidson, I., 2004, In : Acta Crystallographica Section B, Structural Science. B60, 4, p. 461-471 10 p.

    Research output: Contribution to journalArticle

    4 Citations (Scopus)
    2003

    Disordered 2,2 ',3,3 ',4,6,6 '-hepta-O-pivaloyl-alpha,alpha '-trehalose

    Baddeley, T. C., Clow, S. M., Cox, P. J., Davidson, I. G., Murdoch, A. M. & Wardell, J. L., 2003, In : Acta Crystallographica Section E: Structure Reports Online. 59, p. 753-755 3 p.

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Disordered 4,4 '-di-O-isobutyroyl-2,2 ',-3,3 ',6,6 '-hex-O-acetyl-alpha,alpha '-trehalose

    Baddeley, T. C., Clow, S. M., Cox, P. J., Davidson, I. G., Ryder, C. & Wardell, J. L., 2003, In : Acta Crystallographica Section E: Structure Reports Online. 59, p. o848-o850 3 p.

    Research output: Contribution to journalArticle

    Ethyl 1,2,3,4-tetra-O-acetyl-beta-D-glucopyranuronate

    Baddeley, T. C., Davidson, I. G., Skakle, J. M. S. & Wardell, J. L., 2003, In : Journal of Chemical Crystallography. 33, p. 33-38 6 p.

    Research output: Contribution to journalArticle

    2002

    1,2,3,4-Tetra-O-acetyl-alpha-D-glucopyranuronamide

    Baddeley, T. C., Davidson, I. G., Skakle, J. M. S. & Wardell, J. L., Apr 2002, In : Acta Crystallographica Section E: Structure Reports Online. 58, 4, p. o447-o449 3 p.

    Research output: Contribution to journalArticle

    Ditrityl alpha,alpha-trehalose hexaacetate

    Baddeley, T. C., Clow, S. M., Cox, P. J., Davidson, I. G., Howie, R. A. & Wardell, J. L., May 2002, In : Acta Crystallographica Section E: Structure Reports Online. 58, 5, p. o476-o477 2 p.

    Research output: Contribution to journalArticle

    2001

    alpha,alpha-trehalose octaacetate ethyl acetate solvate

    Baddeley, T. C., Clow, S. M., Cox, P. J., McLaughlin, A. M. & Wardell, J. L., 2001, In : Acta Crystallographica Section E: Structure Reports Online. 57, 2 p.

    Research output: Contribution to journalArticle